A Positive Cooperativity Binding Model between Ly49 Natural Killer Cell Receptors and the Viral Immunoevasin m157: KINETIC AND THERMODYNAMIC STUDIES

Natural killer (NK) cells discriminate between healthy and virally infected or transformed cells using diverse surface receptors that are both activating and inhibitory. Among them, the homodimeric Ly49 NK receptors, which can adopt two distinct conformations (backfolded and extended), are of partic...

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Bibliografiske detaljer
Main Authors: Romasanta, Pablo N., Curto, Lucrecia M., Urtasun, Nicolas, Sarratea, María B., Chiappini, Santiago, Miranda, María V., Delfino, José M., Mariuzza, Roy A., Fernández, Marisa M., Malchiodi, Emilio L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931067/
https://ncbi.nlm.nih.gov/pubmed/24379405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.532929
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