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Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex with a Human Major Histocompatibility Complex Class II Molecule

Superantigens are bacterial or viral proteins that elicit massive T cell activation through simultaneous binding to major histocompatibility complex (MHC) class II and T cell receptors. This activation results in uncontrolled release of inflammatory cytokines, causing toxic shock. A remarkable prope...

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Detalhes bibliográficos
Main Authors: Fernández, Marisa M., Guan, Rongjin, Swaminathan, Chittoor P., Malchiodi, Emilio L., Mariuzza, Roy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730046/
https://ncbi.nlm.nih.gov/pubmed/16829512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M603969200
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