Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor β Chain

Superantigens (SAgs) are bacterial or viral toxins that bind MHC class II (MHC-II) molecules and T-cell receptor (TCR) in a nonconventional manner, inducing T-cell activation that leads to inflammatory cytokine production, which may result in acute toxic shock. In addition, the emerging threat of pu...

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Détails bibliographiques
Auteurs principaux: Fernández, Marisa M., Cho, Sangwoo, De Marzi, Mauricio C., Kerzic, Melissa C., Robinson, Howard, Mariuzza, Roy A., Malchiodi, Emilio L.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Protein Structure and Folding
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020726/
https://ncbi.nlm.nih.gov/pubmed/21059660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142471
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