Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1

Aggregation of α-synuclein (αS) is involved in the pathogenesis of Parkinson's disease (PD) and a variety of related neurodegenerative disorders. The physiological function of αS is largely unknown. We demonstrate with in vitro vesicle fusion experiments that αS has an inhibitory function on me...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Kamp, Frits, Exner, Nicole, Lutz, Anne Kathrin, Wender, Nora, Hegermann, Jan, Brunner, Bettina, Nuscher, Brigitte, Bartels, Tim, Giese, Armin, Beyer, Klaus, Eimer, Stefan, Winklhofer, Konstanze F, Haass, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964170/
https://ncbi.nlm.nih.gov/pubmed/20842103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.223
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller