Hexokinases link DJ-1 to the PINK1/parkin pathway

Abstract Background Early onset Parkinson’s disease is caused by variants in PINK1, parkin, and DJ-1. PINK1 and parkin operate in pathways that preserve mitochondrial integrity, but the function of DJ-1 and how it relates to PINK1 and parkin is poorly understood. Methods A series of unbiased high-co...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: David N. Hauser, Adamantios Mamais, Melissa M. Conti, Christopher T. Primiani, Ravindran Kumaran, Allissa A. Dillman, Rebekah G. Langston, Alexandra Beilina, Joseph H. Garcia, Alberto Diaz-Ruiz, Michel Bernier, Fabienne C. Fiesel, Xu Hou, Wolfdieter Springer, Yan Li, Rafael de Cabo, Mark R. Cookson
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-09-01
Colecção:Molecular Neurodegeneration
Assuntos:
Proteomics
RNA-Seq
Metabolomics
Systems biology
Parkinson’s disease
Mitophagy
Acesso em linha:http://link.springer.com/article/10.1186/s13024-017-0212-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados