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DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
Mutations in DJ-1, PINK1 (PTEN-induced putative kinase 1) and parkin all cause recessive parkinsonism in humans, but the relationships between these genes are not clearly defined. One event associated with loss of any of these genes is altered mitochondrial function. Recent evidence suggests that tu...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000675/ https://ncbi.nlm.nih.gov/pubmed/20940149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq430 |
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