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Reduction of PINK1 or DJ‐1 impair mitochondrial motility in neurites and alter ER‐mitochondria contacts

Subcellular distribution of mitochondria in neurons is crucial for meeting the energetic demands, as well as the necessity to buffer Ca(2+) within the axon, dendrites and synapses. Mitochondrial impairment is an important feature of Parkinson disease (PD), in which both familial parkinsonism genes D...

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Bibliografiska uppgifter
I publikationen:J Cell Mol Med
Huvudupphovsmän: Parrado‐Fernández, Cristina, Schneider, Bernadette, Ankarcrona, Maria, Conti, Melissa M., Cookson, Mark R., Kivipelto, Miia, Cedazo‐Mínguez, Ángel, Sandebring‐Matton, Anna
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201361/
https://ncbi.nlm.nih.gov/pubmed/30133157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13815
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