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Reduction of PINK1 or DJ‐1 impair mitochondrial motility in neurites and alter ER‐mitochondria contacts

Subcellular distribution of mitochondria in neurons is crucial for meeting the energetic demands, as well as the necessity to buffer Ca(2+) within the axon, dendrites and synapses. Mitochondrial impairment is an important feature of Parkinson disease (PD), in which both familial parkinsonism genes D...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Parrado‐Fernández, Cristina, Schneider, Bernadette, Ankarcrona, Maria, Conti, Melissa M., Cookson, Mark R., Kivipelto, Miia, Cedazo‐Mínguez, Ángel, Sandebring‐Matton, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201361/
https://ncbi.nlm.nih.gov/pubmed/30133157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13815
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