PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation

Maintaining a pool of functional mitochondria requires degradation of damaged ones within the cell. PINK1 is critical in this quality-control process: loss of mitochondrial membrane potential causes PINK1 to accumulate on the mitochondrial surface, triggering mitophagy. However, little is known abou...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Guardia-Laguarta, Cristina, Liu, Yuhui, Lauritzen, Knut H., Erdjument-Bromage, Hediye, Martin, Brittany, Swayne, Theresa C., Jiang, Xuejun, Przedborski, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733537/
https://ncbi.nlm.nih.gov/pubmed/31300519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1691-18.2019
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