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Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gas

Mitochondrial respiratory deficiencies have been observed in numerous neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases. For decades, these reductions in oxidative phosphorylation (OxPhos) have been presumed to trigger an overall bioenergetic crisis in the neuron, resulting i...

詳細記述

保存先:
書誌詳細
出版年:J Clin Invest
主要な著者: Area-Gomez, Estela, Guardia-Laguarta, Cristina, Schon, Eric A., Przedborski, Serge
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307938/
https://ncbi.nlm.nih.gov/pubmed/30601141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120848
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