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Novel subcellular localization for α-synuclein: possible functional consequences

α-synuclein (α-syn) is one of the genes that when mutated or overexpressed causes Parkinson’s Disease (PD). Initially, it was described as a synaptic terminal protein and later was found to be localized at mitochondria. Mitochondria-associated membranes (MAM) have emerged as a central endoplasmic re...

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Bibliografske podrobnosti
izdano v:Front Neuroanat
Main Authors: Guardia-Laguarta, Cristina, Area-Gomez, Estela, Schon, Eric A., Przedborski, Serge
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337379/
https://ncbi.nlm.nih.gov/pubmed/25755636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2015.00017
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