Biochemical and Morphological Consequences of Human α-Synuclein Expression in a Mouse α-Synuclein Null Background

A consensus about the functions of human wild-type or mutated α-synuclein (αSYN) is lacking. Both forms of αSYN are implicated in Parkinson’s disease, whereas the wild-type form is implicated in substance abuse. Interactions with other cellular proteins and organelles may meditate its functions. We...

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Détails bibliographiques
Auteurs principaux: Prasad, Kavita, Tarasewicz, Elizabeth, Strickland, Pamela A. Ohman, O’Neill, Michael, Mitchell, Stephen N., Merchant, Kalpana, Tep, Samnang, Hilton, Kathryn, Datwani, Akash, Buttini, Manuel, Mueller-Steiner, Sarah, Richfield, Eric K.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072281/
https://ncbi.nlm.nih.gov/pubmed/21272100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07558.x
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