Resistance of α-synuclein null mice to the parkinsonian neurotoxin MPTP

Parkinson's disease (PD) is most commonly a sporadic illness, and is characterized by degeneration of substantia nigra dopamine (DA) neurons and abnormal cytoplasmic aggregates of α-synuclein. Rarely, PD may be caused by missense mutations in α-synuclein. MPTP, a neurotoxin that inhibits mitoch...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dauer, William, Kholodilov, Nikolai, Vila, Miquel, Trillat, Anne-Cecile, Goodchild, Rose, Larsen, Kristin E., Staal, Roland, Tieu, Kim, Schmitz, Yvonne, Yuan, Chao Annie, Rocha, Marcelo, Jackson-Lewis, Vernice, Hersch, Steven, Sulzer, David, Przedborski, Serge, Burke, Robert, Hen, Rene
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137916/
https://ncbi.nlm.nih.gov/pubmed/12376616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172514599
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados