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Critical Role of Truncated α‐Synuclein and Aggregates in Parkinson's Disease and Incidental Lewy Body Disease

The role of Lewy bodies, Lewy neurites and α‐synuclein (αSYN) in the pathophysiology and diagnosis of Parkinson's disease (PD) is unclear. We used postmortem human tissue, a panel of antibodies (Abs) and confocal microscopy to examine the three‐dimensional neurochemical anatomy of the nigrostri...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Prasad, Kavita, Beach, Thomas G., Hedreen, John, Richfield, Eric K.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505643/
https://ncbi.nlm.nih.gov/pubmed/22452578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00597.x
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