Critical Role of Truncated α‐Synuclein and Aggregates in Parkinson's Disease and Incidental Lewy Body Disease

The role of Lewy bodies, Lewy neurites and α‐synuclein (αSYN) in the pathophysiology and diagnosis of Parkinson's disease (PD) is unclear. We used postmortem human tissue, a panel of antibodies (Abs) and confocal microscopy to examine the three‐dimensional neurochemical anatomy of the nigrostri...

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Publicado en:Brain Pathol
Autores principales: Prasad, Kavita, Beach, Thomas G., Hedreen, John, Richfield, Eric K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2012
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505643/
https://ncbi.nlm.nih.gov/pubmed/22452578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00597.x
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