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Toxicokinetics and toxicodynamics of paraquat accumulation in mouse brain

Paraquat (PQ) is a potential human neurotoxicant and is used in models of oxidative stress. We determined the toxicokinetics (TK) and toxicodynamics (TD) of PQ in adult mouse brain following repeated or prolonged PQ exposure. PQ accumulated in different brain regions and reached a plateau after ~18...

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Bibliografski detalji
Glavni autori: Prasad, Kavita, Tarasewicz, Elizabeth, Mathew, Jason, Ohman Strickland, Pamela A., Buckley, Brian, Richardson, Jason R., Richfield, Eric K.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016858/
https://ncbi.nlm.nih.gov/pubmed/19084006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.11.003
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