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Toxicokinetics and toxicodynamics of paraquat accumulation in mouse brain
Paraquat (PQ) is a potential human neurotoxicant and is used in models of oxidative stress. We determined the toxicokinetics (TK) and toxicodynamics (TD) of PQ in adult mouse brain following repeated or prolonged PQ exposure. PQ accumulated in different brain regions and reached a plateau after ~18...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016858/ https://ncbi.nlm.nih.gov/pubmed/19084006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.11.003 |
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