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Dopamine and α-synuclein dysfunction in Smad3 null mice

BACKGROUND: Parkinson's disease (PD) is characterized by dopaminergic neurodegeneration in the substantia nigra (SN). Transforming growth factor-β1 (TGF-β1) levels increase in patients with PD, although the effects of this increment remain unclear. We have examined the mesostriatal system in ad...

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Detalhes bibliográficos
Main Authors: Tapia-González, Silvia, Giráldez-Pérez, Rosa M, Cuartero, M Isabel, Casarejos, M José, Mena, M Ángeles, Wang, Xiao-Fan, Sánchez-Capelo, Amelia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219599/
https://ncbi.nlm.nih.gov/pubmed/21995845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-72
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