Loss-of-Function of Human PINK1 Results in Mitochondrial Pathology and Can Be Rescued by Parkin

Degeneration of dopaminergic neurons in the substantia nigra is characteristic for Parkinson's disease (PD), the second most common neurodegenerative disorder. Mitochondrial dysfunction is believed to contribute to the etiology of PD. Although most cases are sporadic, recent evidence points to...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Exner, Nicole, Treske, Bettina, Paquet, Dominik, Holmström, Kira, Schiesling, Carola, Gispert, Suzana, Carballo-Carbajal, Iria, Berg, Daniela, Hoepken, Hans-Hermann, Gasser, Thomas, Krüger, Rejko, Winklhofer, Konstanze F., Vogel, Frank, Reichert, Andreas S., Auburger, Georg, Kahle, Philipp J., Schmid, Bettina, Haass, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673250/
https://ncbi.nlm.nih.gov/pubmed/17989306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0719-07.2007
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