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Loss-of-Function of Human PINK1 Results in Mitochondrial Pathology and Can Be Rescued by Parkin

Degeneration of dopaminergic neurons in the substantia nigra is characteristic for Parkinson's disease (PD), the second most common neurodegenerative disorder. Mitochondrial dysfunction is believed to contribute to the etiology of PD. Although most cases are sporadic, recent evidence points to...

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書誌詳細
出版年:J Neurosci
主要な著者: Exner, Nicole, Treske, Bettina, Paquet, Dominik, Holmström, Kira, Schiesling, Carola, Gispert, Suzana, Carballo-Carbajal, Iria, Berg, Daniela, Hoepken, Hans-Hermann, Gasser, Thomas, Krüger, Rejko, Winklhofer, Konstanze F., Vogel, Frank, Reichert, Andreas S., Auburger, Georg, Kahle, Philipp J., Schmid, Bettina, Haass, Christian
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673250/
https://ncbi.nlm.nih.gov/pubmed/17989306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0719-07.2007
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