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Separating DNA with different topologies by atomic force microscopy in comparison with gel electrophoresis
Atomic force microscopy, which is normally used for DNA imaging to gain qualitative results, can also be used for quantitative DNA research, at a single-molecular level. Here, we evaluate the performance of AFM imaging specifically for quantifying supercoiled and relaxed plasmid DNA fractions within...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963572/ https://ncbi.nlm.nih.gov/pubmed/20799746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp105603k |
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