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Detecting Solvent-Driven Transitions of poly(A) to Double-Stranded Conformations by Atomic Force Microscopy

We report the results of direct measurements by atomic force microscopy of solvent-driven structural transitions within polyadenylic acid (poly(A)). Both atomic force microscopy imaging and pulling measurements reveal complex strand arrangements within poly(A) induced by acidic pH conditions, with a...

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Detalhes bibliográficos
Main Authors: Ke, Changhong, Loksztejn, Anna, Jiang, Yong, Kim, Minkyu, Humeniuk, Michael, Rabbi, Mahir, Marszalek, Piotr E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711269/
https://ncbi.nlm.nih.gov/pubmed/19348773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3939
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