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The Force-Driven Conformations of Heparin Studied with Single Molecule Force Microscopy
Using single molecule force spectroscopy we examine the response of heparin chains to mechanical stretching. We find that at forces below 200 pN heparin behaves as a simple entropic spring. At ∼200 pN heparin displays a large enthalpic elasticity, which is evident as a pronounced plateau in the forc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1303493/ https://ncbi.nlm.nih.gov/pubmed/14507732 |
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