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Detecting Ultraviolet Damage in Single DNA Molecules by Atomic Force Microscopy

We report detection and quantification of ultraviolet (UV) damage in DNA at a single molecule level by atomic force microscopy (AFM). By combining the supercoiled plasmid relaxation assay with AFM imaging, we find that high doses of medium wave ultraviolet (UVB) and short wave ultraviolet (UVC) ligh...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jiang, Yong, Ke, Changhong, Mieczkowski, Piotr A., Marszalek, Piotr E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948057/
https://ncbi.nlm.nih.gov/pubmed/17483180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.108209
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