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Detecting Ultraviolet Damage in Single DNA Molecules by Atomic Force Microscopy
We report detection and quantification of ultraviolet (UV) damage in DNA at a single molecule level by atomic force microscopy (AFM). By combining the supercoiled plasmid relaxation assay with AFM imaging, we find that high doses of medium wave ultraviolet (UVB) and short wave ultraviolet (UVC) ligh...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948057/ https://ncbi.nlm.nih.gov/pubmed/17483180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.108209 |
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