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Extended, Relaxed, and Condensed Conformations of Hyaluronan Observed by Atomic Force Microscopy

The conformation of the polysaccharide hyaluronan (HA) has been investigated by tapping mode atomic force microscopy in air. HA deposited on a prehydrated mica surface favored an extended conformation, attributed to molecular combing and inhibition of subsequent chain recoil by adhesion to the struc...

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Autores principales: Cowman, Mary K., Spagnoli, Chiara, Kudasheva, Dina, Li, Min, Dyal, Ansil, Kanai, Sonoko, Balazs, Endre A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305036/
https://ncbi.nlm.nih.gov/pubmed/15489305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.049361
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