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Atomic force microscopy captures MutS tetramers initiating DNA mismatch repair

In spite of extensive research, the mechanism by which MutS initiates DNA mismatch repair (MMR) remains controversial. We use atomic force microscopy (AFM) to capture how MutS orchestrates the first step of E. coli MMR. AFM images captured two types of MutS/DNA complexes: single-site binding and loo...

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Detalhes bibliográficos
Main Authors: Jiang, Yong, Marszalek, Piotr E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160242/
https://ncbi.nlm.nih.gov/pubmed/21666597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.180
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