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Atomic force microscopy captures MutS tetramers initiating DNA mismatch repair

In spite of extensive research, the mechanism by which MutS initiates DNA mismatch repair (MMR) remains controversial. We use atomic force microscopy (AFM) to capture how MutS orchestrates the first step of E. coli MMR. AFM images captured two types of MutS/DNA complexes: single-site binding and loo...

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書誌詳細
主要な著者: Jiang, Yong, Marszalek, Piotr E
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160242/
https://ncbi.nlm.nih.gov/pubmed/21666597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.180
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