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A species-generalized probabilistic model-based definition of CpG islands

The DNA of most vertebrates is depleted in CpG dinucleotides, the target for DNA methylation. The remaining CpGs tend to cluster in regions referred to as CpG islands (CGI). CGI have been useful as marking functionally relevant epigenetic loci for genome studies. For example, CGI are enriched in the...

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Sonraí Bibleagrafaíochta
Main Authors: Irizarry, Rafael A., Wu, Hao, Feinberg, Andrew P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962567/
https://ncbi.nlm.nih.gov/pubmed/19777308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-009-9222-5
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