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A species-generalized probabilistic model-based definition of CpG islands

The DNA of most vertebrates is depleted in CpG dinucleotides, the target for DNA methylation. The remaining CpGs tend to cluster in regions referred to as CpG islands (CGI). CGI have been useful as marking functionally relevant epigenetic loci for genome studies. For example, CGI are enriched in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Irizarry, Rafael A., Wu, Hao, Feinberg, Andrew P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962567/
https://ncbi.nlm.nih.gov/pubmed/19777308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-009-9222-5
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