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Redefining CpG islands using hidden Markov models
The DNA of most vertebrates is depleted in CpG dinucleotide: a C followed by a G in the 5′ to 3′ direction. CpGs are the target for DNA methylation, a chemical modification of cytosine (C) heritable during cell division and the most well-characterized epigenetic mechanism. The remaining CpGs tend to...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883304/ https://ncbi.nlm.nih.gov/pubmed/20212320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxq005 |
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