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A species-generalized probabilistic model-based definition of CpG islands

The DNA of most vertebrates is depleted in CpG dinucleotides, the target for DNA methylation. The remaining CpGs tend to cluster in regions referred to as CpG islands (CGI). CGI have been useful as marking functionally relevant epigenetic loci for genome studies. For example, CGI are enriched in the...

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Detalhes bibliográficos
Main Authors: Irizarry, Rafael A., Wu, Hao, Feinberg, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962567/
https://ncbi.nlm.nih.gov/pubmed/19777308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-009-9222-5
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