Molecular Mechanism of Terbinafine Resistance in Saccharomyces cerevisiae

Ten mutants of the yeast Saccharomyces cerevisiae resistant to the antimycotic terbinafine were isolated after chemical or UV mutagenesis. Molecular analysis of these mutants revealed single base pair exchanges in the ERG1 gene coding for squalene epoxidase, the target of terbinafine. The mutants di...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Leber, Regina, Fuchsbichler, Sandra, Klobučníková, Vlasta, Schweighofer, Natascha, Pitters, Eva, Wohlfarter, Kathrin, Lederer, Mojca, Landl, Karina, Ruckenstuhl, Christoph, Hapala, Ivan, Turnowsky, Friederike
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC296195/
https://ncbi.nlm.nih.gov/pubmed/14638499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.12.3890-3900.2003
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares