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Effect of Lipid Particle Biogenesis on the Subcellular Distribution of Squalene in the Yeast Saccharomyces cerevisiae

Squalene belongs to the group of isoprenoids and is a precursor for the synthesis of sterols, steroids, and ubiquinons. In the yeast Saccharomyces cerevisiae, the amount of squalene can be increased by variation of growth conditions or by genetic manipulation. In this report, we show that a hem1Δ mu...

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Bibliographic Details
Main Authors: Spanova, Miroslava, Czabany, Tibor, Zellnig, Günther, Leitner, Erich, Hapala, Ivan, Daum, Günther
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825407/
https://ncbi.nlm.nih.gov/pubmed/20032462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074229
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