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Influence of squalene on lipid particle/droplet and membrane organization in the yeast Saccharomyces cerevisiae

In a previous study (Spanova et al., 2010, J. Biol. Chem., 285, 6127–6133) we demonstrated that squalene, an intermediate of sterol biosynthesis, accumulates in yeast strains bearing a deletion of the HEM1 gene. In such strains, the vast majority of squalene is stored in lipid particles/droplets tog...

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Detalhes bibliográficos
Main Authors: Spanova, Miroslava, Zweytick, Dagmar, Lohner, Karl, Klug, Lisa, Leitner, Erich, Hermetter, Albin, Daum, Günther
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Pub. Co 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790963/
https://ncbi.nlm.nih.gov/pubmed/22342273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2012.01.015
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