A Recombinant Influenza A Virus Expressing an RNA-Binding-Defective NS1 Protein Induces High Levels of Beta Interferon and Is Attenuated in Mice

Previously we found that the amino-terminal region of the NS1 protein of influenza A virus plays a key role in preventing the induction of beta interferon (IFN-β) in virus-infected cells. This region is characterized by its ability to bind to different RNA species, including double-stranded RNA (dsR...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Donelan, Nicola R., Basler, Christopher F., García-Sastre, Adolfo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296096/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.24.13257-13266.2003
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!