A Recombinant Influenza A Virus Expressing an RNA-Binding-Defective NS1 Protein Induces High Levels of Beta Interferon and Is Attenuated in Mice
Previously we found that the amino-terminal region of the NS1 protein of influenza A virus plays a key role in preventing the induction of beta interferon (IFN-β) in virus-infected cells. This region is characterized by its ability to bind to different RNA species, including double-stranded RNA (dsR...
محفوظ في:
| الحاوية / القاعدة: | J Virol |
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| المؤلفون الرئيسيون: | , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
2003
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296096/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.24.13257-13266.2003 |
| الوسوم: |
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