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Respiratory Syncytial Virus (RSV) Nonstructural (NS) Proteins as Host Range Determinants: a Chimeric Bovine RSV with NS Genes from Human RSV Is Attenuated in Interferon-Competent Bovine Cells

Bovine respiratory syncytial virus (BRSV) escapes from cellular responses to alpha/beta interferon (IFN-α/β) by a concerted action of the two viral nonstructural proteins, NS1 and NS2. Here we show that the NS proteins of human RSV (HRSV) are also able to counteract IFN responses and that they have...

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Detalhes bibliográficos
Main Authors: Bossert, Birgit, Conzelmann, Karl-Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155099/
https://ncbi.nlm.nih.gov/pubmed/11932394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4287-4293.2002
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