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Role of Alpha/Beta Interferons in the Attenuation and Immunogenicity of Recombinant Bovine Respiratory Syncytial Viruses Lacking NS Proteins

Alpha/beta interferons (IFN-α/β) are not only a powerful first line of defense against pathogens but also have potent immunomodulatory activities. Many viruses have developed mechanisms of subverting the IFN system to enhance their virulence. Previous studies have demonstrated that the nonstructural...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Valarcher, Jean-Francois, Furze, Julie, Wyld, Sara, Cook, Roy, Conzelmann, Karl-Klaus, Taylor, Geraldine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165239/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12857912/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.15.8426-8439.2003
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