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Role of Alpha/Beta Interferons in the Attenuation and Immunogenicity of Recombinant Bovine Respiratory Syncytial Viruses Lacking NS Proteins

Alpha/beta interferons (IFN-α/β) are not only a powerful first line of defense against pathogens but also have potent immunomodulatory activities. Many viruses have developed mechanisms of subverting the IFN system to enhance their virulence. Previous studies have demonstrated that the nonstructural...

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Main Authors: Valarcher, Jean-Francois, Furze, Julie, Wyld, Sara, Cook, Roy, Conzelmann, Karl-Klaus, Taylor, Geraldine
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC165239/
https://ncbi.nlm.nih.gov/pubmed/12857912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8426-8439.2003
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