Role of Alpha/Beta Interferons in the Attenuation and Immunogenicity of Recombinant Bovine Respiratory Syncytial Viruses Lacking NS Proteins

Alpha/beta interferons (IFN-α/β) are not only a powerful first line of defense against pathogens but also have potent immunomodulatory activities. Many viruses have developed mechanisms of subverting the IFN system to enhance their virulence. Previous studies have demonstrated that the nonstructural...

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Detalles Bibliográficos
Main Authors: Valarcher, Jean-Francois, Furze, Julie, Wyld, Sara, Cook, Roy, Conzelmann, Karl-Klaus, Taylor, Geraldine
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC165239/
https://ncbi.nlm.nih.gov/pubmed/12857912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8426-8439.2003
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