Role of Alpha/Beta Interferons in the Attenuation and Immunogenicity of Recombinant Bovine Respiratory Syncytial Viruses Lacking NS Proteins

Alpha/beta interferons (IFN-α/β) are not only a powerful first line of defense against pathogens but also have potent immunomodulatory activities. Many viruses have developed mechanisms of subverting the IFN system to enhance their virulence. Previous studies have demonstrated that the nonstructural...

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Bibliografische gegevens
Hoofdauteurs: Valarcher, Jean-Francois, Furze, Julie, Wyld, Sara, Cook, Roy, Conzelmann, Karl-Klaus, Taylor, Geraldine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Vaccines and Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC165239/
https://ncbi.nlm.nih.gov/pubmed/12857912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8426-8439.2003
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