Bovine Respiratory Syncytial Virus Nonstructural Proteins NS1 and NS2 Cooperatively Antagonize Alpha/Beta Interferon-Induced Antiviral Response

The functions of bovine respiratory syncytial virus (BRSV) nonstructural proteins NS1 and NS2 were studied by generation and analysis of recombinant BRSV carrying single and double gene deletions. Whereas in MDBK cells the lack of either or both NS genes resulted in a 5,000- to 10,000-fold reduction...

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Main Authors: Schlender, Jörg, Bossert, Birgit, Buchholz, Ursula, Conzelmann, Karl-Klaus
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC116331/
https://ncbi.nlm.nih.gov/pubmed/10954520
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