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Bovine Respiratory Syncytial Virus Nonstructural Proteins NS1 and NS2 Cooperatively Antagonize Alpha/Beta Interferon-Induced Antiviral Response

The functions of bovine respiratory syncytial virus (BRSV) nonstructural proteins NS1 and NS2 were studied by generation and analysis of recombinant BRSV carrying single and double gene deletions. Whereas in MDBK cells the lack of either or both NS genes resulted in a 5,000- to 10,000-fold reduction...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schlender, Jörg, Bossert, Birgit, Buchholz, Ursula, Conzelmann, Karl-Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC116331/
https://ncbi.nlm.nih.gov/pubmed/10954520
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