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Tumor Suppressor Action of Liganded Thyroid Hormone Receptor β by Direct Repression of β-Catenin Gene Expression

The abundance of β-catenin, which plays a critical role in oncogenesis, is tightly controlled by proteasomal pathways. Its aberrant accumulation is associated with the overactivation of its oncogenic signaling and tumorigenesis in cancers, including thyroid cancer. Our previous studies have suggeste...

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Détails bibliographiques
Auteurs principaux: Guigon, Celine J., Kim, Dong Wook, Zhu, Xuguang, Zhao, Li, Cheng, Sheue-yann
Format: Artigo
Langue:Inglês
Publié: The Endocrine Society 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954723/
https://ncbi.nlm.nih.gov/pubmed/20844001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0475
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