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NOVEL ONCOGENIC ACTIONS OF TRβ MUTANTS IN TUMORIGENESIS

The thyroid hormone, T3, plays important roles in metabolism, growth, and differentiation. Germline mutations in thyroid hormone receptor beta (TRβ) have been identified in many individuals with resistance to thyroid hormone, a syndrome of reduced sensitivity to T3. A close association of somatic mu...

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Detalhes bibliográficos
Main Authors: Guigon, Celine J, Cheng, Sheue-yann
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716728/
https://ncbi.nlm.nih.gov/pubmed/19391168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.180
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