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NOVEL ONCOGENIC ACTIONS OF TRβ MUTANTS IN TUMORIGENESIS

The thyroid hormone, T3, plays important roles in metabolism, growth, and differentiation. Germline mutations in thyroid hormone receptor beta (TRβ) have been identified in many individuals with resistance to thyroid hormone, a syndrome of reduced sensitivity to T3. A close association of somatic mu...

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Bibliographic Details
Main Authors: Guigon, Celine J, Cheng, Sheue-yann
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716728/
https://ncbi.nlm.nih.gov/pubmed/19391168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.180
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