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Novel Nongenomic Signaling of Thyroid Hormone Receptors in Thyroid Carcinogenesis
The thyroid hormone receptors (TRs) are transcription factors that mediate the pleiotropic activities of the thyroid hormone, T3. Four T3-binding isoforms, TRα1, TRβ1, TRβ2, and TRβ3, are encoded by two genes, THRA and THRB. Mutations and altered expression of TRs have been reported in human cancers...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2744088/ https://ncbi.nlm.nih.gov/pubmed/19549593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2009.01.007 |
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