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Novel Nongenomic Signaling of Thyroid Hormone Receptors in Thyroid Carcinogenesis

The thyroid hormone receptors (TRs) are transcription factors that mediate the pleiotropic activities of the thyroid hormone, T3. Four T3-binding isoforms, TRα1, TRβ1, TRβ2, and TRβ3, are encoded by two genes, THRA and THRB. Mutations and altered expression of TRs have been reported in human cancers...

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Библиографические подробности
Главные авторы: Guigon, Celine J, Cheng, Sheue-yann
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744088/
https://ncbi.nlm.nih.gov/pubmed/19549593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2009.01.007
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