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Characterization of skeletal phenotypes of TRα1(PV) and TRβ(PV) mutant mice: implications for tissue thyroid status and T3 target gene expression

Bone development is extremely sensitive to alterations in thyroid status. Recently, we analyzed the skeletal phenotypes of mice with the dominant negative resistance to thyroid hormone (RTH) mutation PV targeted to either the thyroid hormone receptor (TR) α1 or β gene. This perspective summarizes ou...

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書誌詳細
主要な著者: O'Shea, Patrick J., Bassett, J.H. Duncan, Cheng, Sheue-yann, Williams, Graham R.
フォーマット: Artigo
言語:Inglês
出版事項: The Nuclear Receptor Signaling Atlas 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513065/
https://ncbi.nlm.nih.gov/pubmed/16862217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1621/nrs.04011
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