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Tumor Suppressor Action of Liganded Thyroid Hormone Receptor β by Direct Repression of β-Catenin Gene Expression

The abundance of β-catenin, which plays a critical role in oncogenesis, is tightly controlled by proteasomal pathways. Its aberrant accumulation is associated with the overactivation of its oncogenic signaling and tumorigenesis in cancers, including thyroid cancer. Our previous studies have suggeste...

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Detalhes bibliográficos
Main Authors: Guigon, Celine J., Kim, Dong Wook, Zhu, Xuguang, Zhao, Li, Cheng, Sheue-yann
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954723/
https://ncbi.nlm.nih.gov/pubmed/20844001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0475
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