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Reactivation of the Silenced Thyroid Hormone Receptor β Gene Expression Delays Thyroid Tumor Progression

That a knock-in mouse harboring a dominant-negative thyroid hormone receptor (TR)-β (Thrb) mutation develops metastatic thyroid cancer strongly suggests the involvement of TRβ in carcinogenesis. Epigenetic silencing of the THRB gene is common in human cancers. The aim of the present study was to det...

詳細記述

保存先:
書誌詳細
主要な著者: Kim, Won Gu, Zhu, Xuguang, Kim, Dong Wook, Zhang, Lisa, Kebebew, Electron, Cheng, Sheue-yann
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529371/
https://ncbi.nlm.nih.gov/pubmed/23183175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1728
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