Chargement en cours...

Differential Recruitment of Nuclear Coregulators Directs the Isoform-Dependent Action of Mutant Thyroid Hormone Receptors

Studies using mice deficient in thyroid hormone receptors (TR) indicate that the two TR isoforms, TRα1 and TRβ1, in addition to mediating overlapping biological activities of the thyroid hormone, T3, also mediate distinct functions. Mice harboring an identical dominant negative mutation (denoted PV)...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Fozzatti, Laura, Lu, Changxue, Kim, Dong-Wook, Cheng, Sheue-yann
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100599/
https://ncbi.nlm.nih.gov/pubmed/21474540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0474
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!