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Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α
Genetic evidence from patients with mutations of the thyroid hormone receptor α gene (THRA) indicates that the dominant negative activity of mutants underlies the pathological manifestations. However, the molecular mechanisms by which TRα1 mutants exert dominant negative activity in vivo are not cle...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651436/ https://ncbi.nlm.nih.gov/pubmed/23610395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222334110 |
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